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Popular Brands Hospira (Pfizer) Cyanocobalamin Injection American Regent Cyanocobalamin Fresenius Kabi Cyanocobalamin Sandoz Cyanocobalamin Teva Cyanocobalamin Strengths 1000 mcg/mL (standard adult & clinical dose) 500 mcg/mL (pediatric or dose-adjusted therapy) 2000 mcg/mL (high-strength for severe deficiency) Typical regimen: 1000 mcg IM weekly, then monthly maintenance (per healthcare providers direction)

2012, Pickart & Margolina 2018, Li et al

Primary research areas Senolytic research models

Patients suffering from major depression had reduced levels of immunoreactive DSIP compared to control subjects, as shown in cerebrospinal fluid (CSF) analysis

Slow titration lowers the acute burden