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Fatigue may result from multiple factors including significant caloric deficit from appetite suppression, metabolic adaptation to weight loss, nutritional deficiencies, gastrointestinal side effects affecting food and fluid intake, and changes in blood glucose levels
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In the OASIS 1 clinical trial, participants taking high-dose oral semaglutide (50mg) lost an average of 15.1% of their body weight over 68 weeks
Rotate injection sites (abdomen, thighs, upper arms) to prevent local irritation and lipohypertrophy
Treatment measures were clearly described in 17 patients
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