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MOTS-c (New England Peptide, USA) was administered daily at 5 or 15 mg/kg via intraperitoneal injections
A 2025 meta-analysis in JAMA Psychiatry found no increase in depression or suicidality with GLP-1 medications versus placebo
Instead, it manufactures compounded medications that are distributed through healthcare providers, telehealth platforms, and pharmacy networks
Older adults (65+) require closer monitoring for medication interactions, kidney function, and medication tolerance
Accumulated clinical evidence suggests that GLP-1RAs not only show no increase in pancreatic cancer risk among diabetic patients but potentially confer a protective effect [26]
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