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In SUSTAIN 6, a placebo-corrected heart rate increase of 2.75 beats per minute (bpm) was observed for semaglutide 0.5 mg, and 3.2 bpm for the 1.0 mg dosage (97)
Wegovy is approved for obesity treatment and weight loss, while Mounjaro is approved for managing blood sugar in type 2 diabetes
Human risk is unknown Important limits Animal studies cannot establish safe liver effects or monitoring rules for people
GLP-1 medications can suppress appetite, so under-eating becomes a real risk especially for people already conditioned to restrict
GLP-1 Friendly Badges While the FDA primarily regulates foods and supplements, the US Department of Agriculture handles meat and poultry products about 20% of the food supply and require premarket approval of labels that make health claims such as GLP-1 Friendly. Food marketing claims targeting GLP-1 users have grown rapidly since 2024 as companies including Five companies have submitted 21 approval requests for labels describing meat or poultry-related foods as GLP-1 Friendly or for a GLP-1 Lifestyle, according to USDAs data as of June 2
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