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Multinomial LASSO was performed across 1,000 resampled multimorbidity pattern membership datasets derived from the LCA models, retaining those biomarkers selected in at least 70% of the models as repeatedly associated with multimorbidity patterns (Extended Data Fig

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Marcadores de inflamacin sistmica, tales como protena C reactiva (PCR) y su regulador intermedio, la interleucina 6 (IL-6), se asocian transversalmente con la sensibilidad a la insulina y la funcin de las clulas