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Some, like Jaws, Relentless Predator or Daretti, Scrap Savant have direct artifact synergies while others simply appreciate the burn aiding their fast game plan

Note that Tinybones also draws you cards on each turn, and when they discard to each other as well

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Those include ones with powerful EtB effects, powerful ongoing effects, ones that dominate the board and ones that are really hard to deal with

If you already have enough stuff to get you to five mana then Thragtusk is a good final nail in the coffin in the role of life gainer while also rarely being a dead spell in any match up